ISDE has released a new guideline on the management of clinically staged cT2N0M0 esophageal cancer, an area where treatment decisions have often lacked clear direction.
Following a systematic review and expert panel process using the GRADE methodology, the guideline gives a conditional recommendation for neoadjuvant therapy followed by surgery over primary surgical resection for most adult patients.
The guideline also notes that surgery alone may remain appropriate for selected patients, particularly those unable to tolerate neoadjuvant treatment or those at low risk of lymph node metastasis.
This new guidance is intended to support multidisciplinary teams and patients in making evidence-based treatment decisions.
ISDE also recognizes the outstanding work of the ISDE Guidelines Committee chaired by Bas Wijnhoven (Erasmus MC - University Medical Center Rotterdam, The Netherlands) and Ewen Griffiths (Queen Elizabeth Hospital, Birmingham, UK). Members of this committee continue to assess emerging evidence and develop important guidelines and consensus statements that advance global standards in esophageal disease care.
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